Discoveries in Cancer Chemotherapy

In the current scenario, the most commonly used types of cancer treatment are chemotherapy, radiotherapy, tumor surgery, and hormonal therapy. Small molecule inhibitors are being extensively studied for precise target treatment. Their extremely small size allows them to diffuse through the plasma membrane and interact with the cytoplasmic domain of cell-surface receptors and intracellular signaling molecules that eventually blocks cancer cell proliferation. The application of genomic data in the field of oncology has given an insight into genetic modifications and epigenetic modifications such as chromatin-modification and DNA Methylation. Use of bioinformatics and proteomics has further speeded up the drug discovery process in cancer.

  • Small molecule inhibitors as cancer therapeutics
  • Tumor angiogenesis inhibition
  • Chemotherapy induced autophagy
  • Oncogenomics in drug design
  • Oncoproteomics based drug development

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