DNA Repair Mechanism

DNA repair is a collection of processes by which a cell identifies and corrects damage to the DNA molecules that encode its genome. In human cells, both normal metabolic activities and environmental factors such as UV light and radiation can cause DNA damage, resulting in as many as 1 million individual molecular lesions per cell per day. Many of these lesions cause structural damage to the DNA molecule and can alter or eliminate the cell's ability to transcribe the gene that the affected DNA encodes. Other lesions induce potentially harmful mutations in the cell's genome, which affect the survival of its daughter cells after it undergoes mitosis. As a consequence, the DNA repair process is constantly active as it responds to damage in the DNA structure. When normal repair processes fail, and when cellular apoptosis does not occur, irreparable DNA damage may occur, including double-strand breaks and DNA cross linkages .The rate of DNA repair is dependent on many factors, including the cell type, the age of the cell, and the extracellular environment. A cell that has accumulated a large amount of DNA damage, or one that no longer effectively repairs damage incurred to its DNA, can enter one of three possible states.

DNA Repair is a collection of processes by which a cell identifies and corrects damage to the DNA molecules that encode its genome. As a consequence, the DNA repair process is constantly active as it responds to damage in the DNA structure. When normal repair processes fail, and when cellular apoptosis does not occur, irreparable DNA damage may occur, including double-strand breaks and DNA cross linkages. The types of repair mechanisms are:  Base excision pair, Mismatch repair, Nucleotide excision repair.

  • DNA Double Strand Break Repair
  • Base excision pair
  • Flipping out mechanism
  • Mismatch repair
  • Nucleotide excision repair
  • DNA polymerase proof reading
  • Transpositions

Related Conference of DNA Repair Mechanism

August 15-16, 2018

16th Asia Pacific Biotechnology Congress

Singapore
August 27-28, 2018

5th International Conference on Glycobiology & Glycoproteomics

Toronto, Ontario, Canada
August 27-28, 2018

3rd International Conference on Molecular Biology & Nucleic Acids

Toronto, Ontario, Canada
September 17-19, 2018

4th Glycobiology World Congress

Rome, Italy
September 24-26, 2018

14th International Conference on Structural Biology

Berlin, Germany
October 03-04, 2018

4th International Conference on Biochemistry & Metabolomics

Los Angeles, California, USA
October 18-19, 2018

10th International Congress on Structural Biology

Helsinki, Finland
November 19-20, 2018

15th World Congress on

Structural Biology

Paris, France
February 28-March 01, 2019

5th International Conference on Enzymology and Protein Chemistry

Berlin, Germany

22nd Global Congress on Biotechnology

February 28-March 02, 2019 Berlin, Germany

DNA Repair Mechanism Conference Speakers

Recommended Sessions

Related Journals

Are you interested in