Drug addiction Pathophysiology

The primary factor in addiction mechanism is Neurophysiologic reinforcement. Addiction related brain and behaviour disorders, which include psychiatric diagnoses, like schizophrenia, mania, depressive disorder, and obsessive-compulsive disorder. Medical recognition of addiction, accept as a medical disorder, and treatment options for addiction is noticed in schizophrenia, manic illness disorder, and major depressive disorder. Similarly, major questions concern of pathology of addiction including the genetic and environmental factors, neurochemical and neurogenic changes, and the course of the illness.

The reward pathway affects our neuropsychological transmissions, and this pathway disturbs instinctual drives also malfunctions. This process is associated with drug, food, sex addiction, and compulsive disorders including attention-deficit hyperactivity disorder. In normal person neurotransmitters, which includes dopamine, that acts "off switch mechanism" fulfil an instinctual drive. Individuals who are disposed to become addicted shown to have a different gene that causes this reward system to malfunction. These people experience the change in level of neurochemical change in reward system when fulfilling an instinctual drive, and there is no "off switch mechanism” they have become seen.

  • Neurotransmitters in Drug addiction
  • Addiction on Therapeutic efficacy
  • Chronic nicotine activates stress
  • Mesocorticolimbic pathway
  • Dopamine and glutamate
  • Chronic alcoholism
  • Organic psychosis

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