Drug Designing and Biomarkers
Drug designing is an inventive process to find new medication centred on the knowledge of biological target. Drug is most commonly a small molecule that inhibits or activates the function of a biomolecule, which in turn outcomes in a therapeutic benefit to the patient. Drug design commonly but not essentially relies on computational techniques. This type of modelling is often mentioned to as computer-aided drug design.
A biomarker is an attribute that can be studied as an indicator of pathogenic and biological operation along with pharmacological retort to a therapeutic involvement. They indicate either normal or diseased activity in the body. Biomarkers are specific molecules, genes, gene products, hormones, cells or enzymes.
- Drug targets
- Ligand-based design
- Structure-based design
- Computer-aided drug design
- Scoring functions
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