Drug Discovery and Integrative Biology

Drug discovery is the process through which potential new medicines are identified. It involves a wide range of scientific disciplines, including biology, chemistry and pharmacology. Modern drug discovery involves the identification of Enzyme inhibitors in drug discovery, Strategies and challenges in drug discovery and Dynamics of structure based drug discovery, selectivity (to reduce the potential of side effects), efficacy/potency, metabolic stability (to increase the half-life), and oral bioavailability. Once a compound that fulfills all of these requirements has been identified, it will begin the process of drug development prior to clinical trials. One or more of these steps may, but not necessarily, involve computer-aided drug design. Cancer and drug discovery involves Multi target paradigm in drug discovery with unique Systems approach for drug discovery from herbal medicine. Discovering drugs that may be a commercial success, or a public health success, involves a complex interaction between investors, industry, academia, patent laws, regulatory exclusivity, marketing and the need to balance secrecy with communication. Meanwhile, for disorders whose rarity means that no large commercial success or public health effect can be expected, the orphan drug funding process ensures that people who experience those disorders can have some hope of pharmacotherapeutic advances like Anti-fungal drug discovery and In vitro method evaluation in drug discovery to name the major few. Drug Discovery research has the major growing market with applications in pharmaceuticals and medicine and thus major companies like Bristol-Myers Squibb Company, Isis Pharmaceuticals, Inc. , Merck & Co. Inc. and Johnson & Johnson focusing on the growing industry. Without a doubt it has become a primarily subject with increasing interest and thus more than 150 universities have come up with the curriculum; to be majorly mentioned as University of Bath, University of Dundee, University of Birmingham, The University of Edinburgh and Drexel University College of Medicine.
  • Enzyme inhibitors in drug discovery
  • Anti-fungal drug discovery
  • In vitro method evaluation in drug discovery
  • Strategies and challenges in drug discovery
  • Systems approach for drug discovery from herbal medicine
  • Dynamics of structure based drug discovery
  • Cancer and drug discovery
  • Multi target paradigm in drug discovery

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