Drug targeting

 

    The new drug target discovery and exploitation is a key for both the pharmaceutical industry and academic research. To ensure an insight into trends in the exploitation of new drug targets analysed the drugs that were approved by the US Food and Drug Administration.The main drawbacks in systemic drug administration are Lack of drug affinity towards the pathological site and nonspecific toxicity and other adverse effects so drug targeting may resolve some these problems.  For therapeutic and cosmetic modification of hair, we have developed a hair-follicle-selective macromolecule and small molecule targeting system with topical application of phosphatidylcholine-based liposomes. Liposome-entrapped melanins, proteins, genes, and small-molecules have been selectively targeted to the hair follicle and hair shafts of mice. Liposomal delivery of these molecules is time dependent. Negligible amounts of delivered molecules enter the dermis, epidermis, or bloodstream thereby demonstrating selective follicle delivery. Naked molecules are trapped in the stratum corneum and are unable to enter the follicle molecular and macromolecular drugs including the design and characterization of carrier systems (whether colloidal, protein or polymeric) for both vitro and/or in vivo applications of these drugs. Papers are not restricted to drugs delivered by way of a carrier, but also include studies on molecular and macromolecular drugs that are designed to target specific cellular or extra-cellular molecules.. 

  • Magnetic drug targeting in cancer
  • Recent advancements in drug targeting
  • Recent Approaches to Drug Targeting
  • Drug Discovery and Development
  • Rational Drug Design
  • Novel approaches to drug targeting

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Drug targeting Conference Speakers