Emerging Technology in Natural Product Drug Development

The development of natural product-derived drugs poses significant challenges in several areas. Of prime concern is the supply of the drug in sufficient quantities to permit preclinical, and hopefully clinical, development, and ultimately, if given a successful, clinical outcome, commercial production. Another major challenge is that of formulation. Natural products generally are highly insoluble in aqueous media, and such solubility is a prime requirement for administration of the drug to human patients, particularly through the intravenous route commonly used in the treatment of cancer patients. 

Drug discovery within the pharmaceutical industry, with few exceptions, is based on the high throughput screening (HTS) of tens of thousands of compounds a week, using enzyme or receptor-based assays designed to uncover compounds with specific mechanisms of action.50 This poses a dual problem for natural products screening. In the first place, crude natural product extracts are complex mixtures, containing hundreds of compounds, often including polyphenolic compounds such as plant tannins
Natural products have also been evaluated by several cheminformatic methods in recent years. Feher and Schmidt showed that natural products have better drug-like properties than a random sample of compounds prepared by combinatorial chemistry.

  • High-Throughput Screening
  • Combinatorial Chemistry
  • Combinatorial Chemistry
  • Bioinformatics, Proteomics and Genomics

Related Conference of Emerging Technology in Natural Product Drug Development

August 31-September 01, 2017,

3rd International Conference on Biopharmaceutics and Biologic Drugs

Philadelphia, USA
(10 Plenary Forums - 1Event)
August 31-September 01, 2017

5th International Pharmacy Conference


(10 Plenary Forums - 1 Event)
Philadelphia, USA
September 04-06, 2017

9th World Congress on Pharmacology

Paris, France
September 11-13, 2017

4th International Conference on Clinical Trials

San Antonio, Texas, USA
(10 Plenary Forums - 1 Event)
September 11-12, 2017

World Congress on Biotherapeutics and Bioanalytical Techniques

(10 Plenary Forums - 1Event) Dallas, Texas, USA
September 18-19, 2017

6th International Conference on Forensic Research & Technology

(10 Plenary Forums - 1Event)
Houston, Texas, USA
Sep 25-26, 2017

12th Annual
Pharma Middle East Congress

Dubai, UAE
October 02-03, 2017

9th Annual Pharmaceutical Chemical Analysis Congress

Vienna, Austria
October 16-17, 2017

16th Annual Medicinal & Pharmaceutical Sciences Congress

Seoul, South Korea
October 16-18, 2017
(10 Plenary Forums - 1 Event)

4th International Conference on Past and Present Research Systems of Green Chemistry

Atlanta, Georgia, USA
October 18-19, 2017

6th Global Congress on Mass Spectrometry

Osaka, Japan
October 19-20, 2017

9th Annual Congress on Drug Design & Drug Formulation

Seoul, South Korea
October 19-20, 2017

4th International Conference and Exhibition on Pain Medicine

(10 Plenary Forums - 1 Event)
San Francisco, California, USA
(10 Plenary Forums - 1 Event) October 23-24, 2017

5th International Conference on Clinical Pharmacy and Healthcare IT

Orlando, Florida, USA
October 30-November 01, 2017
A B2B Networking & Global Knowledge Exchange Forum

Annual Congress on Emerging Orphan Drugs and  Rare Diseases

San Antonio, Texas, USA
November 13-14, 2017

Global Experts Meeting on Toxicology

Singapore
November 23-24, 2017

Annual Meeting on Pharmacology

Dubai, UAE
March 19-20, 2018

International Meeting on Nutraceuticals

Singapore
April 26-27, 2018

11th European Biosimilars Congress

Rome, Italy
May 07-09, 2018

10th Annual European Pharma Congress

Frankfurt, Germany
June 18-19, 2018

9th Global Experts Meeting on Neuropharmacology

Paris, France
June 20-22, 2018

7th World Congress on Mass Spectrometry

Rome, Italy
July 09-10, 2018

12th Global
Pharmacovigilance & Clinical Trials Summit

Sydney, Australia
July 16-18, 2018

15th Asia-Pacific Pharma Congress

Melbourne, Australia
August 13-14, 2018

Global Experts Meeting on Case Reports

Tokyo, Japan
September 13-14, 2018

7th World Congress on Chromatography

Prague, Czech Republic

Emerging Technology in Natural Product Drug Development Conference Speakers

Recommended Sessions

Related Journals

Are you interested in