Emerging Trends in Ophthalmic Drug Delivery

The principal challenge in advancing therapeutics for treating diseases of the front as well as back of the eye is attainment of effective drug concentration at the drug target for prolonged periods of time, whilst minimizing any side effects. In addition, enhancing patient adherence with drug therapy, especially for asymptomatic diseases such as glaucoma, poses another challenge. there is an urgent need to develop novel ocular delivery systems that meet the multimedication needs of the elderly with pre-existing visual and motor impairment. The ideal ocular delivery system is one that is easy to manufacture, allows noninvasive self-administration, achieves and maintains effective drug concentrations at the target site for desired time intervals, minimizes systemic exposure and affords good patient comfort, acceptance and compliance. While eye drops may be ideal for treating anterior segment eye diseases, it may not be the most reliable drug delivery vehicle entrusted with targeted drug delivery to the posterior segment.  Advancements in visual inserts gives a technique to beat the physical obstructions that routinely avoided adequate treatment. Embed advances territory are underneath improvement allowing everlasting medication conveyance from one system, these gadgets allowed back chamber infections to be totally treated.

  • Ocular pharmacokinetic studies & barriers to ocular drug delivery
  • Contact lenses for ocular drug delivery
  • Scleral lens delivery systems
  • Liposome-loaded contact lenses
  • Binocular Treatment of Amblyopia Using Videogames (BRAVO)
  • Intravitreal implants
  • Ocuserts and Lacriserts
  • Microemulsion
  • Ocular Iontophoresis
  • Microspheres and Nanoparticles
  • Hydrogel Contact Lens
  • Collagen Shield

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