Endocrine Complications

Endocrine disorders are often quite complex, involving a mixed picture of hyposecretion and hypersecretion because of the feedback mechanisms involved in the endocrine system. For example, most forms of hyperthyroidism are associated with an excess of thyroid hormone and a low level of thyroid stimulating hormone. Patients with multi-transfused thalassemia major may develop severe endocrine complications due to iron overload. The anterior pituitary is particularly sensitive to iron overload which disrupts hormonal secretion resulting in hypogonadism, short stature, acquired hypothyroidism and hypoparathyroidism. Glucose intolerance and diabetes mellitus are also common in thalassaemic patients. Delayed or absent puberty and hypogonadism may result in fertility problems which affect enormously the life of thalassemics. Glucose intolerance in adolescence and diabetes mellitus later in life are also frequent complications mainly due to iron overload, chronic liver disease and genetic predisposition. Primary hypothyroidism and hypoparathyroidsm usually appear in the second decade of life; are related to iron overload and may be reversible at an early stage by intensive chelation. Osteopenia and osteoporosis due to a complicated pathogenesis represent prominent causes of morbidity in young adults of both genders with thalassaemia. Early recognition and prevention of the endocrine complications, by early and regular chelation therapy, is mandatory for the improvement of the quality of life and psychological outcome of these patients.

    Related Conference of Endocrine Complications

    November 25-26, 2019

    International Conference on Diabetes and Cholesterol Metabolism

    MENA Plaza Hotel Albarsha | Dubai, UAE
    December 04-05, 2019

    3rd Annual Congress on Diabetes and Its Complications

    Tokyo, Japan
    December 9,10,2019

    International Congress and Expo on Diabetic Care

    Bangkok,Thailand
    December 12-13, 2019

    Annual Congress on Diabetes and Endocrinology

    Dubai, UAE
    March 25-26, 2020

    29th World Diabetes & Heart Congress

    | Tokyo, Japan
    April 13-14, 2020

    World congress on Endocrinology and Metabolic syndrome

    Auckland, New Zealand
    April 17-18, 2020

    3rd Global Meeting on Diabetes and Endocrinology

    Kualalumpur, Malaysia
    June 15-16, 2020

    29thEuropean Diabetes Congress

    Barcelona, Spain
    July 06-07, 2020

    Annual Congress on Diabetes, Metabolism and Obesity

    Sydney, Australia
    July 15-16, 2020

    28th International Diabetes and Healthcare Conference

    Helsinki, Finland
    August 17-18, 2020

    16th World Congress on Endocrinology & Diabetes

    | Copenhagen, Denmark
    August 24-25, 2020

    Global Summit On Diabetes & Endocrinology

    Kyoto, Japan
    Sept 22-23, 2020

    2nd Asia Pacific Endocrinology Congress

    | Singapore
    October 12-13, 2020

    2nd Global Congress on Endocrinology and Gynaecology

    Sydney, Australia
    October 14-15, 2020

    World Congress on Endocrinology & Diabetes

    Rome, Italy
    October 30-31, 2020

    Annual Summit on Metabolomics

    Vancouver, Canada
    November 16-17-2020

    World congress and Expo on Diabetes

    Kyoto, Japan
    November 16-17, 2020

    2nd Asia Pacific Diabetes and Endocrinology Congress

    Brisbane, Australia
    June 14-15, 2021

    diabetic 2021

    Abu Dhabi, UAE

    Endocrine Complications Conference Speakers

    Recommended Sessions

    Related Journals

    Are you interested in