Environmental toxins and Parkinson’s disease

1‐methyl‐4‐phenyl tetrahydropyridine, a contaminant of a synthetic opiate, can result in PD through its neurotoxic metabolite. Drinking well water, rural life style and agricultural practices have been identified as the major risk factors. As per the statistical review, individuals from the agricultural background have found increased levels of organochlorine pesticides in their brains. Beside this people in welding works, defence activities and industrial areas are also prone to parkinsonism.

  • Dopamine agonists
  • Anticholinergics
  • COMT inhibitors

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