Etiology and Pathogenesis of Kidney Diseases

The cause of chronic kidney disease isn't always known. But any condition or disease that damages blood vessels or other structures in the kidneys can lead to kidney disease. The conditions that can damage the kidneys and cause chronic kidney disease include:

Kidney diseases and infections, such as polycystic kidney disease, pyelonephritis, glomerulonephritis, or a kidney problem you were born with.

Having a narrowed or blocked renal artery. A renal artery carries blood to the kidneys.

Long-term use of medicines that can damage the kidneys. Examples include non-steroidal anti-inflammatory drugs (NSAIDs), such as celecoxib and ibuprofen, and certain antibiotics.

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