Exemplification of Patients

Atherosclerosis remains a major cause of death in industrialized countries. In vivo visualization of the atherosclerotic plaque and its components (calcifications, fibro cellular tissue, lipid core, haemorrhage, and thrombus), particularly in humans, will further elucidate the disease process and the effect of various types of interventions, and subsequently will have important clinical implications. Recently, angiography and ultrasound were the most common methods of analysing atherosclerotic disease. Angiography provides information on the degree of stenosis but only limited information on the morphology of the atherosclerotic plaque. Ultrasound is able to visualize the plaque and to demonstrate the presence of calcifications.

Atherosclerosis remains a major cause of death in industrialized countries. In vivo visualization of the atherosclerotic plaque and its components (calcifications, fibro cellular tissue, lipid core, haemorrhage, and thrombus), particularly in humans, will further elucidate the disease process and the effect of various types of interventions, and subsequently will have important clinical implications. Recently, angiography and ultrasound were the most common methods of analysing atherosclerotic disease. Angiography provides information on the degree of stenosis but only limited information on the morphology of the atherosclerotic plaque. Ultrasound is able to visualize the plaque and to demonstrate the presence of calcifications.

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