Exosomes

There are many circulating components found in biofluid but the one gaining significant attention is ExosomesExosomes are extracellular vesicles released from cells when an intermediate endocytic compartment fuses with the plasma membrane. It is found in almost all biological fluids like blood, urine, saliva, serum, breast milk etc. These acts as a mediator of cell to cell communication as they transfer bioactive molecules like lipids, nucleic acids, proteins etc. to the other cells.  As they carry important molecular information like nucleic acid and protein they show the source of cell and indicate if there is any presence of abnormal cells, hence acting as a Biomarker.

Fusion of plasma membrane and endocytic compartment releases components called Exosomes responsible for cell to cell communication. These transfer informational components like nucleic acid, protein, lipids etc. from one cell to another which reflects the source of the cell. This trait makes them a potential Biomarker. They are present in almost all of the biofluids like urine, serum, breast milk etc.  

 

  • Exosomes and nanotheranostics.
  • Exosome-based approaches for diagnosis of cancers like: Colorectal Cancer and gastrointestinal cancer.
  • Exosomes and diagnosis of diseases like prion diseases, Epstein–Barr virus (EBV), kidney-related diseases etc.
  • Circulating Exosomes as new biomarkers for neurodegenerative disease or brain injury diagnosis.
  • Exosomal biomarkers for monitoring immunological rejection of tissue grafts.
  • Exosomal microRNAs as biomarkers.

Related Conference of Exosomes

Exosomes Conference Speakers