Gastrointestinal Cancer: Signs & Symptoms

Signs and symptoms of gastrointestinal cancer includes nausea, vomiting, frequent heartburn, loss of appetite (sometimes accompanied by sudden weight loss), early satiety (feeling full after eating only a small amount), bloody stools, jaundice (a yellowish discoloration in the eyes and skin),excessive fatigue,Weight loss not associated with changes in diet, enlarged liver, stomach pain (which may be worse after meals)

Sporadic (Nonhereditary) Colorectal Cancer is detected through screening procedures or when the patient presents with symptoms. Screening is important for prevention and should be a part of routine care for adults over the age of 50 who are at low-risk. High-risk individuals (those who are with previous colon cancer, those who have family history of colon cancer, and those who have inflammatory bowel disease or history of colorectal polyps) require careful follow-up. Major advances have been made in our understanding of molecular events leading to the formation of adenomatous polyps and cancer most of the colorectal cancers are sporadic.

  • Sporadic Colorectal Cancer
  • Familial adenomatous polyposis
  • Lynch Syndrome or Hereditary Nonpolyposis Colorectal Cancer (HNPCC)
  • Microsatellite instability
  • Molecular pathogenesis

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