Gastrointestinal Stromal Tumors

Some of the drugs in the pipeline for colorectal cancer therapeutics are Lonsurf, CYRAMZA (ramucirumab), TS-1/Teysuno, CPP-1X (eflornithine hydrochloride), MelCancerVac, Xilonix, and Nintedanib. There are various medications such as chemotherapy drugs, immunotherapy, and leucovorin (chemoprotectant) that can be used to treat colorectal cancer. Chemotherapy drugs for the treatment of colorectal cancer include anti-metabolites such as fluorouracil and capecitabine. Monoclonal antibodies used in immunotherapy as part of the treatment of colorectal cancer are bevacizumab, cetuximab, and panitumumab. Bevacizumab (Avastin®), ramucirumab (Cyramza®), and ziv-aflibercept (Zaltrap®) are drugs used for colon cancer that target vascular endothelial growth factor (VEGF). VEGF is a protein that helps tumors form new blood vessels to get nutrients (a process known as angiogenesis).

Analysis from business intelligence provider GBI Research - Colorectal Cancer Therapeutics in Major Developed Markets to 2020 - states that the Colorectal Cancer (CRC) treatment market value will increase at a moderate Compound Annual Growth Rate (CAGR) of 1.8%, from $8.3 billion in 2013 to $9.4 billion by 2020.Bevacizumab and ramucirumab are monoclonal antibodies, which are man-made versions of immune system proteins. These drugs are typically combined with chemo to treat advanced colon cancer.
 
Ziv-aflibercept is a different kind of protein that targets VEGF. It can also be combined with chemo to treat advanced colon cancer, although it was approved to be combined only with a certain chemo combination.These drugs are given as infusions into a vein (IV) every 2 or 3 weeks.
 
 
  • Drugs used for Pancreatic & Colorectal Cancer
  • Current therapeutic approaches
  • Novel therapeutic antibodies to treat colorectal cancer
  • Colorectal Cancer Therapeutics Market: Global Industry Analysis
  • Adverse drug reactions

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