Genetic and Cellular Toxicology

Genetic toxicology is the study of the chemical and physical effects on genetic material. It includes the study of DNA damage in living cells that leads to cancer, but it also examines changes in DNA that can be inherited from one generation to the next. The permanent, inherited changes can affect either somatic cells of the organism or germ cells to be passed on to future generations. Cells prevent expression of the genotoxic mutation by either DNA repair or apoptosis; however, the damage may not always be fixed leading to mutagenesis.

Cells are the smallest single units in organs that altogether define organ function. Organs are made of many different cell types. Chemical substances and their metabolites may affect the function of different cells in different organs, with each affected cells resulting in different pathological consequences. Heavy metals can be bound to substances such as sulphur, and in doing so have the potential to be toxic to most of the body’s cells.

  • Biological toxicology
  • Carcinogens and cancer
  • Gentotoxicity
  • Cytotoxicity
  • Mutagenicity
  • Systemic toxicology

Related Conference of Genetic and Cellular Toxicology

October 04-05, 2018 London, UK

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Genetic and Cellular Toxicology Conference Speakers

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