Genetic Toxicology and Toxicity Testing

The heredity of living organisms is majorly affected by chemical, physical and biological agents. The effects of these are studied under genetic toxicology. All the research and study information is stored as electronic data in web-based resources such as National Library of Medicine (NLM), which includes MEDLINE®, PUBMED®, TOXNET®, Gateway and also Entrez. The major application of genetic testing is that of predicting the drugs which possess high cancer-causing potential. This  saves a lot of time and resources for the pharmaceutical companies and also assists in carving out safer drug products. 

Genetic toxicology has numerous applications in the field of hazard identification and risk assessment. The techniques used include, Comet assay, Single-Cell Gel Electrophoresis Technique etc. The testing techniques used include Bacterial Reverse Mutation Assay, in vitro Toxicology Testing and in vivo Testing. Genetic toxicology testing also plays a major role in the study of carcinogenic substances. Genotoxic chemotherapy is a technique in which cancer is treated using genotoxic drugs.

  • Pre-Clinical Toxicity Testing
  • Chemotherapy
  • Gentotoxicity and Mutagenicity
  • In Vitro Toxicity Testing
  • Alternatives to Animal Testing
  • Genetic Risk Estimation
  • In vitro and In vivo Comet Assays
  • Mutations and Cancer

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