Genetical effects in otorhinolaryngology

Molecular genetics is a rapidly expanding field with possibilities for novel diagnostic and treatment strategies for otorhinolaryngological diseases. Sensorineural hearing loss (SNHL) is one of the most common disabilities in humans and congenital hearing loss is the most common congenital abnormality in the new born. Genetic factors contribute to about 50–60 % of otorhinolaryngological disorders . Allelic mutations in some genes can cause recessive and dominant mutations in the same gene or may cause syndromic or non-syndromic  hearing loss and allergic reactions.

  • Gene therapy
  • Genetic heterogeneity
  • Congenital hearing loss
  • Autosomal recessive deafness
  • Allelic mutations

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