Hepatitis Antibodies

Hepatitis is an inflammation of your liver, often caused by an infection. About 95 percent of hepatitis infections are caused by one of five viruses: hepatitis A, B, C, D, or E and the symptoms of all of these infections are similar. Immune system makes IgM antibodies when you are first infected with HAV. It can take 14 to 50 days to develop symptoms of hepatitis A after you become infected. IgM antibodies usually begin to appear in your blood five to 10 days before you start having symptoms and can stay in your blood for about six months after the infection. Autoimmune hepatitis is a chronic inflammatory disease in which the immune system attacks healthy liver cells causing damage to the organ. There are three types of autoimmune hepatitis based upon the presence of antibodies in the blood.         
Type 1 have antinuclear and smooth muscle antibodies      
Type 2 show liver-kidney-microsomal antibodies     
Type 3 (is currently not regarded as a clinically distinct AIH subgroup) display SLA/LP antibodies.
Autoimmune hepatitis is a chronic hepatitis characterized by immunologic and auto immunologic features, generally including the presence of circulating autoantibodies and a high total serum gamma globulin, usually confined to the IgG fraction [1]. Most cases respond to anti-inflammatory or immunosuppressive therapy.

The main circulating autoantibodies, although not specific for the disease, are antinuclear antibodies (ANA) and anti-smooth muscle antibodies (ASMA) in type 1 disease and, in type 2 autoimmune hepatitis, anti-liver-kidney microsome-1 antibodies (ALKM-1) and anti-liver cytosol antibody-1 (ALC-1).

  • Hepatitis B Surface Antibodies
  • Hepatitis B Core Antibodies
  • Advances in Hepatitis C Antibodies Tests

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