Hybrid Approaches for Structure Prediction

Hybrid Approaches for Structure Prediction

Structural bioinformatics is the special practical result for protein structure determination. Structural Bioinformatics is an interdisciplinary field that deals with the three-dimensional structures of biomolecules. It attempts to model and discover the basic principles underlying biological machinery at the molecular level. It is based on the hypothesis that 3D structural information of a biological system is the basic to understanding its mechanism of action and function. Structural bioinformatics combines applications of physical and chemical principles with algorithms from computational science. Major areas protein and nucleic acid 3D structure determination, prediction of protein 3D structure from sequence, protein structure validation protein structure comparison and alignment, protein and nucleic acid structure classification inferring protein function from structure, prediction of protein-ligand interaction, prediction of protein-protein interactions, development of databases.

  • Primary Structure
  • Tertiary Structure
  • Secondary Structure
  • Quatenary Structure

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