Hypersensitivity and Autoimmunity

Hypersensitivity is a set of undesirable reactions produced by the normal immune system, including allergies and autoimmunity. These reactions may be damaging, uncomfortable, or occasionally fatal. Hypersensitivity reactions require a pre-sensitized state of the host. Hypersensitivity is abnormal or pathologic immune reaction that is caused by an immune response to repeated exposure to an antigen. Hypersensitivity diseases include autoimmune diseases, in which immune responses are directed against self-antigens, and that result from uncontrolled or excessive responses to foreign antigens. Many of the autoimmune diseases have a hypersensitivity reaction as part of their pathogenesis these diseases include hay fever, food allergies, atopic dermatitis, allergic asthma, and anaphylaxis.

Hypersensitivity describes an abnormal or pathologic immune reaction that is caused by an immune response to repeated exposure to an antigen. Hypersensitivity diseases include autoimmune diseases, in which immune responses are directed against self-antigens, and diseases that result from uncontrolled or excessive responses to foreign antigens. Because these reactions tend to occur against antigens that cannot be escaped (i.e. self-antigens) and because of positive feedback systems intrinsic to various aspects of the immune response, hypersensitivity diseases tend to manifest as chronic problems.

  • Allergy
  • Immune complex and Autoreaction
  • Hypersensitivity and chronic diseases
  • Hypersensitvity products
  • Autoantibodies
  • Inflammation
  • Hypersensitivity Reaction

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