Immune Checkpoints

The immune system plays a dual role against cancer: it prevents tumor cell outgrowth and also sculpts the immunogenicity of the tumor cells. Cancer cells are able to escape from the immune system by inhibiting T lymphocytes activation. New immunotherapies have been developed to target these T lymphocytes activation modulators: the immune checkpoints, defined as molecules of immune system that either turn up a signal or turn down a signal. Most of the cancers protect themselves from immune system by inhibiting activation of T cell.

 These novel therapies are showing promising results with durable objective responses in some patients. Ipilimumab (anti-CTLA4) was the first of these new therapeutics to be approved by the FDA in March 2011 for advanced melanoma and other immunomodulators trials are ongoing in other cancers with similar encouraging results like with the anti PD-1/PD-L1. These drugs are already challenging our future practice like for evaluation of tumor response or for management of immune related toxicities. Many immune checkpoints have been identified and could potentially be targeted. Future studies will help to identify predictive factors but also to coordinate these new immunotherapies with our classic treatment strategies.

  • Immune checkpoint therapy
  • Immune modulators
  • Inhibitory immune checkpoints
  • Stimulatory immune checkpoints
  • Anti tumor immune response

Related Conference of Immune Checkpoints

June 29-July 01, 2017

8th European Immunology Conference

Madrid, Spain
July 03-05, 2017

9th Asia-Pacific Global Summit on Healthcare & Immunology

Kuala Lumpur, Malaysia
July 12-13, 2017

3rd World Conference on Parasitology & Pathogenesis

Chicago, Illinois, USA
September 01-02, 2017

4th International Conference on Parasitology

Prague, Czech Republic
September 11-12, 2017

7th World Congress on Immunology

Amsterdam, Netherlands
November 2-3, 2017

9th World Congress and Expo on Immunology

Atlanta, Georgia, USA
November 02-03, 2017

9th World Congress on Immunity, Inflammation and Immunotherapies

Atlanta, Georgia, USA
November 06-07, 2017

2nd International Conference on Autoimmunity

Frankfurt, Germany
November 08-09, 2017

3rd Antibodies and Bio Therapeutics Congress & B2B

Las Vegas, Nevada, USA
November 13-14, 2017

5th International Conference on HIV/AIDS, STDs and STIs

Las Vegas, Nevada, USA
Dec 14-15, 2017

World Immunology Congress

Dubai, UAE
April 16-17, 2018

EuroSciCon Conference on StemCell

Amsterdam, Netherlands
July 05-07, 2018

EuroSciCon Conference on Immunology

Vienna, Austria

Immune Checkpoints Conference Speakers

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