Immunity and Host defence

Immune system is categorized into non-specific and specific response. Innate immunity is integral and is mobilized following the infection. Innate is termed non-specific because the protective response is the same regardless of the initiating infection. This is in contrast to the adaptive immune system which is slower, responds specifically, and generates an immunological memory.

The primary component of innate immunity is inflammation. Injured cells release cytokines and other pro-inflammatory factors like bradykinin, histamine, leukotriene, prostaglandins, and serotonin to contain the spread of infection and promote healing. These pro-inflammatory mediators induce vasodilatation and attract phagocytes. Neutrophils subsequently increase the response by attracting lymphocytes and leukocytes. Activation of the Complement cascade enhances the innate response.

An important consequence of complement cascade activation is opsonization. Opsonization of pathogenic antigens tags invasive microorganisms for ingestion and destruction by phagocytes. Though innate response involves a wide range of cell types but is mostly dependent on basophils, mast cell, neutrophils and macrophages. Another important function of the innate immune system is to stimulate the adaptive immune response via antigen presentation.

  • Physical barriers
  • Inflammation
  • Acute phase reactions
  • Innate immunity
  • Acquired immunity
  • Immunization
  • Complement system

Related Conference of Immunity and Host defence

November 2-3, 2017

9th World Congress and Expo on Immunology

Atlanta, Georgia, USA
November 02-03, 2017

9th World Congress on Immunity, Inflammation and Immunotherapies

Atlanta, Georgia, USA
November 06-07, 2017

2nd International Conference on Autoimmunity

Frankfurt, Germany
November 08-09, 2017

3rd Antibodies and Bio Therapeutics Congress & B2B

Las Vegas, Nevada, USA
November 13-14, 2017

5th International Conference on HIV/AIDS, STDs and STIs

Las Vegas, Nevada, USA
Dec 14-15, 2017

World Immunology Congress

Dubai, UAE
April 19-20, 2018

7th World Congress on Immunology

Amsterdam, Netherlands
May 28-29, 2018

World Congress on Allergy and Immunotherapy

Osaka, Japan

9th European Immunology Conference

June 14-16, 2018 Rome, Italy
July 05-07, 2018

EuroSciCon Conference on Immunology Conference 2018

Vienna, Austria
July 12-13, 2018

5th International Conference on Parasitology

Paris, France

Immunity and Host defence Conference Speakers

Recommended Sessions

Related Journals

Are you interested in