Immunological Variability

The host immune system retains immunological memory of B and T cells stimulated by previous infections. Upon later inoculation, a host rapidly builds defense from its memory cells. Each host acquires a unique memory profile based on its infection history.

With respect to the antigenic response of pathogen, the host varies genetically. MHC alleles are highly polymorphic. The germ line genes that contribute to the T cell receptor have some polymorphisms that influence recognition, but the germ line B cell receptor genes do not carry any known polymorphisms.

The immune profiles of host system describe the degree of distribution of specific antigenic variants. Host systems that are previously affected by the pathogen tend to have broader profiles as these are experienced with infections. Maternal antibodies provide short-term resistance to infants, and certain antibody along with TCR provides temporary protection to recently infected hosts. The host system may vary spatially in their prior exposure to different epitopes, creating a spatial mosaic in the selective pressures that favor different antigenic variants.

  • Immunodominance
  • Tissue regeneration in autoimmunity
  • Cross reactivity of antigens
  • Immunological memory

Related Conference of Immunological Variability

November 2-3, 2017

9th World Congress and Expo on Immunology

Atlanta, Georgia, USA
November 02-03, 2017

9th World Congress on Immunity, Inflammation and Immunotherapies

Atlanta, Georgia, USA
November 06-07, 2017

2nd International Conference on Autoimmunity

Frankfurt, Germany
November 08-09, 2017

3rd Antibodies and Bio Therapeutics Congress & B2B

Las Vegas, Nevada, USA
November 13-14, 2017

5th International Conference on HIV/AIDS, STDs and STIs

Las Vegas, Nevada, USA
Dec 14-15, 2017

World Immunology Congress

Dubai, UAE
April 19-20, 2018

7th World Congress on Immunology

Amsterdam, Netherlands
May 28-29, 2018

World Congress on Allergy and Immunotherapy

Osaka, Japan

9th European Immunology Conference

June 14-16, 2018 Rome, Italy
July 05-07, 2018

EuroSciCon Conference on Immunology Conference 2018

Vienna, Austria
July 12-13, 2018

5th International Conference on Parasitology

Paris, France

Immunological Variability Conference Speakers

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