In-vitro and In-vivo Toxicology

In vivo toxicology studies are carried out to assess the severity on onset, duration of toxic effects, degree of reversibility and dose dependency. In vitro toxicity testing is a scientific method of analysis for toxic chemical substances on cultured mammalian cell lines or bacterial cell lines. In vitro testing is carried out to identify the chemicals which are potentially hazardous and to confirm the lacking toxic properties at initial stages of development for new possibly useful therapeutic drugs. In vivo toxicological studies are carried out on multiple species such as rodents, guinea pig, rabbits through different routes of exposure such as topical, intravenous, intramuscular etc.

 

Toxicological testing methods are useful for the testing of toxicity of the particular drug or the chemical. Toxicological testing methods are also called as the safety assessment studies which are used to test the safety of the drug. It is conducted by researchers using standard test procedures to comply with the governing regulations. Toxicological testing methods are the part of the pre-clinical testing procedures. The important methods include the In-vitro and In-vivo toxicological testing methods.

 

  • In-vitro Methods
  • In-vivo Methods
  • Preclinical Drug Development
  • Toxocological Testing
  • Predictive Toxicology

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