Innovative Therapeutic Apporaches in Breast Cancer

Targeted Therapies is one of the innovative in breast cancer treatment. Several clinical trials led by physician-scientists at Mass General are revealing the power of new targeted anticancer therapies in breast cancer. Everolimus is a targeted therapy that works by zeroing in on the mTOR protein, which is regulated by the family of enzymes known as PI3 kinases (PI3K). In healthy cells, mTOR is involved in cell growth, cell proliferation, protein synthesis, and many other functions. In tumor cells, the mTOR pathway goes awry, leading to excess proliferation and a failure to respond to normal growth regulatory mechanisms. Everolimus in postmenopausal hormone-receptor-positive advanced breast cancer.

Surgery for Breast Cancer is really challenging to cure the breast cancer without any side effects. Lumpectomy is Surgery to remove the tumor along with some surrounding healthy tissue, leaving the margins (tissue bordering the tumor) free from cancer. Quadrantectomy is a breast-conserving surgery, this procedure removes one-fourth of the breast tissue. Mastectomy is a surgery to remove all the breast tissue. The most common type of mastectomy today is called a modified radical mastectomy, in which the breast tissue is removed but the muscles in the chest wall are spared, preserving arm strength. Lymphadenectomy is a surgery to remove one or more lymph nodes in the tumor area. Nodes are then examined for cancer by our pathology department. Oophorectomy is a removing the female ovaries to decrease hormone production. Plastic and Reconstructive Surgery are the surgeries to restore or improve the appearance of the breast. Some women choose to have reconstruction surgery at the time of a mastectomy; others defer a decision about reconstruction until a later time.

Several clinical trials led by physician-scientists at Mass General are revealing the power of new targeted anticancer therapies in breast cancer.

Routine Cancer Genotyping
To help guide the administration of appropriate targeted therapies for women seeking treatment for advanced breast cancer at Mass General Cancer Center, physicians have established a routine cancer genotyping program—the SNaPshot molecular fingerprinting technique—that assesses each patient’s tumor for known genetic mutations. 

Partial Breast Irradiation
Many women who choose not to have a mastectomy instead undergo breast-conserving surgery where only the tumor and a small margin of tissue are removed, followed by a six-week course of daily radiation to the whole breast. But many women find this lengthy course of treatment represents a significant burden in their daily lives. 

Proton Beam Radiation
In other efforts to limit radiation-induced side effects such as cardiotoxicity, Mass General radiation oncologists are now recruiting women into a pilot clinical trial using proton beam radiation, instead of the standard photon beam. Studies performed at Mass General demonstrated that proton beam irradiation exposes the heart to one-tenth the radiation of photon beam radiation.

Limiting Lymphedema
Physicians in the Mass General Breast Service offer women a new approach to help prevent the onset of lymphedema—a condition affecting 10 percent of women after aggressive breast cancer surgery. Starting in 2005, physicians began a screening program for all women to identify swelling at its earliest stage.

Surgical Advances

Two surgical advances available at Mass General are helping reduce complications and improve cosmetic appearance after breast cancer surgery.

  • New trends to find breast cancer early
  • Determining the best ways for hormonal therapy
  • Anti- angiogenesis, Genetic risk and genetic testing (BRCA etc)
  • Finding new Reconstructive Surgery Approaches
  • Management of DCIS and ADH
  • Molecular Cancer Therapeutics
  • Targeted Therapies
  • Surgery for Breast Cancer
  • Developing ways to evaluate the Genes and Proteins in various Breast Cancer

Related Conference of Innovative Therapeutic Apporaches in Breast Cancer

July 03-05, 2017

9th Asia Pacific Global Summit on Healthcare & Immunology

Kuala Lumpur, Malaysia
July 10-12, 2017

23rd World Nursing and Healthcare Conference

Golden Tulip Berlin - Hotel Hamburg, Berlin, Germany
July 10-11, 2017

36th Cardiovascular Nursing & Nurse Practitioners Meeting

Chicago, Illinois, USA
July 17-18, 2017

25th Cancer Nursing & Nurse Practitioners Conference

Lisbon, Portugal
July 20-22, 2017

4th World Congress on Midwifery and Women’s Health

Melbourne, Australia
July 24-26, 2017

25th World Congress on Nursing Care

Melbourne, Australia
August 21-22, 2017

4th Annual Congress & Medicare Expo on Primary Healthcare

San Francisco, California, USA
August 28-30, 2017

29th World Neonatal Nursing and Maternal Healthcare Congress

Philadelphia, Pennsylvania, USA
Aug 28-30, 2017

2nd World Congress on Midwifery and Women’s Health

Philadelphia, Pennsylvania, USA
August 31- September 02, 2017

26th World Nursing Education Conference

Prague, Czech Republic
September 04-06, 2017, Edinburgh, Scotland

30th World Congress on Advanced Nursing Practice

September 04-05, 2017

28th International Conference on Pediatric Nursing and Healthcare

Edinburgh, Scotland
September 11-13, 2017

28th International Conference on Family Nursing and Healthcare

San Antonio,Texas, USA
September 25-26, 2017

35th Global Nursing Care and Education Conference

Atlanta, Georgia ,USA
September 28-29, 2017

23rd World Nurse Practitioner Conference

Dubai, UAE
October 02-04, 2017

4th International Conference on Gynecology & Obstetrics


TRYP BARCELONA AEROPUERTO, Barcelona, Spain
October 12-14, 2017

Global Nursing Care and Practitioners Meeting

Osaka, Japan
(10Plenary Forums - 1Event)
October 16-18, 2017,

6th World Congress on Breast Cancer & Therapy

Hotel- Crown Plaza San Francisco Airport, San Francisco, CA
October 20-21, 2017

37th Asia-Pacific Nursing and Medicare Summit

Osaka, Japan
October 23-25, 2017

33rd Nursing and Healthcare
Congress

Toronto, Canada
October 23-25, 2017

Global Experts Meeting on Midwifery and Womens Health

Seoul, South Korea
October 26-28, 2017

32nd Euro Nursing & Medicare
Summit

Paris, France
November 08-09, 2017

34thInternational Nurse Education & Nurse Specialist Conference

New Orleans, Louisiana, USA
Dec 06-07, 2017

46th Global Nursing and Healthcare Conference

Sao Paulo, Brazil
December 11-13, 2017

45th World Congress on Nursing Care

Rome, Italy
December 21-23, 2017

Nursing & Healthcare Congress

Dallas, USA
June 07-09, 2018 London, UK

World Congress on Polycystic Ovarian Syndrome

March 01-03, 2018

46th Global Nursing & Healthcare Conference

London, UK
March 21-23, 2018

20th Global Nursing Education Conference

New York, USA
April 16-17, 2018

World Congress on Nursing and Health Care

Dubai, UAE
November 13-15, 2018

Nursing & Midwifery- 2018

London, UK
July 16-17, 2018

7th World Congress on Breast Cancer

Melbourne, Australia
July 16-18, 2018

21st World Nursing Education Conference

Melbourne, Australia

Innovative Therapeutic Apporaches in Breast Cancer Conference Speakers

Recommended Sessions

Related Journals

Are you interested in