Innovative Therapeutic Apporaches in Breast Cancer

Targeted Therapies is one of the innovative in breast cancer treatment. Several clinical trials led by physician-scientists at Mass General are revealing the power of new targeted anticancer therapies in breast cancer. Everolimus is a targeted therapy that works by zeroing in on the mTOR protein, which is regulated by the family of enzymes known as PI3 kinases (PI3K). In healthy cells, mTOR is involved in cell growth, cell proliferation, protein synthesis, and many other functions. In tumor cells, the mTOR pathway goes awry, leading to excess proliferation and a failure to respond to normal growth regulatory mechanisms. Everolimus in postmenopausal hormone-receptor-positive advanced breast cancer.

Surgery for Breast Cancer is really challenging to cure the breast cancer without any side effects. Lumpectomy is Surgery to remove the tumor along with some surrounding healthy tissue, leaving the margins (tissue bordering the tumor) free from cancer. Quadrantectomy is a breast-conserving surgery, this procedure removes one-fourth of the breast tissue. Mastectomy is a surgery to remove all the breast tissue. The most common type of mastectomy today is called a modified radical mastectomy, in which the breast tissue is removed but the muscles in the chest wall are spared, preserving arm strength. Lymphadenectomy is a surgery to remove one or more lymph nodes in the tumor area. Nodes are then examined for cancer by our pathology department. Oophorectomy is a removing the female ovaries to decrease hormone production. Plastic and Reconstructive Surgery are the surgeries to restore or improve the appearance of the breast. Some women choose to have reconstruction surgery at the time of a mastectomy; others defer a decision about reconstruction until a later time.

Several clinical trials led by physician-scientists at Mass General are revealing the power of new targeted anticancer therapies in breast cancer.

Routine Cancer Genotyping
To help guide the administration of appropriate targeted therapies for women seeking treatment for advanced breast cancer at Mass General Cancer Center, physicians have established a routine cancer genotyping program—the SNaPshot molecular fingerprinting technique—that assesses each patient’s tumor for known genetic mutations. 

Partial Breast Irradiation
Many women who choose not to have a mastectomy instead undergo breast-conserving surgery where only the tumor and a small margin of tissue are removed, followed by a six-week course of daily radiation to the whole breast. But many women find this lengthy course of treatment represents a significant burden in their daily lives. 

Proton Beam Radiation
In other efforts to limit radiation-induced side effects such as cardiotoxicity, Mass General radiation oncologists are now recruiting women into a pilot clinical trial using proton beam radiation, instead of the standard photon beam. Studies performed at Mass General demonstrated that proton beam irradiation exposes the heart to one-tenth the radiation of photon beam radiation.

Limiting Lymphedema
Physicians in the Mass General Breast Service offer women a new approach to help prevent the onset of lymphedema—a condition affecting 10 percent of women after aggressive breast cancer surgery. Starting in 2005, physicians began a screening program for all women to identify swelling at its earliest stage.

Surgical Advances

Two surgical advances available at Mass General are helping reduce complications and improve cosmetic appearance after breast cancer surgery.

  • New trends to find breast cancer early
  • Determining the best ways for hormonal therapy
  • Anti- angiogenesis, Genetic risk and genetic testing (BRCA etc)
  • Finding new Reconstructive Surgery Approaches
  • Management of DCIS and ADH
  • Molecular Cancer Therapeutics
  • Targeted Therapies
  • Surgery for Breast Cancer
  • Developing ways to evaluate the Genes and Proteins in various Breast Cancer

Related Conference of Innovative Therapeutic Apporaches in Breast Cancer

July 27-28, 2018

7th Annual Congress on Primary Healthcare, Nursing and Neonatal Screening

Vancouver, British Columbia, Canada
August 08-09, 2018

28th Surgical Nursing & Nurse Education Conference

Osaka, Japan
August 13-14, 2018

Annual Child and Family Healthcare Nursing Conference

Bali, Indonesia
August 16-18, 2018
Crowne Plaza Madrid Airport, Madrid, Spain

31st World Congress on Advanced Nursing Practice

August 21-23, 2018

25th Global Nursing & Health Care Conference

Paris, France
August 22-23, 2018

5th Asia Pacific
Gynecology and Obstetrics Congress

Tokyo, Japan
August 22-23, 2018

47th World Congress on Nursing & Health Care

Singapore
August 29-30, 2018

36th Global Nursing Care & Education Conference

Boston, Massachusetts, USA
August 29-30, 2018

17th World Congress on Clinical Nursing and Practice

Hotel Hilton Zurich Airport, Zurich, Switzerland
September 13-15, 2018

24th World Nursing and Healthcare Conference

Park Inn by Radisson, Copenhagen, Denmark
September 13-15, 2018

Annual Emergency Medicine and Acute Care Conference

Dubai, UAE
Sep 14-15, 2018

Annual Congress on Nursing Pharmacology

Prague, Czech Republic
September 14-15, 2018

28th Annual Congress on Nursing Education and Research

Prague, Czech Republic
September 21-22, 2018;

3rd International Conference on Perinatal Nursing & Adolescent Psychiatry

Pacific Gateway Hotel at Vancouver Airport, British Columbia,Vancouver, Canada
September 21-22, 2018

18th World Congress on Clinical Nursing and Practice

Panorama Hotel Prague Milevská 7, 140 63 Praha 4, Czechia Prague, Czech Republic
September 21-22, 2018;

3rd International Conference on Pediatric Nursing & Healthcare

Pacific Gateway Hotel at Vancouver Airport, Vancouver, British Columbia, Canada
September 26-27, 2018

3rd World Congress on Mother & Neonatal Nursing Care

Chicago, Illinois, USA
October 01-02, 2018 |

5th World Congress on Midwifery & Womens Health

Frankfurt, Germany
October 03-04, 2018

38thAsia-Pacific Nursing and Medicare Summit

Osaka, Japan
October 04-05, 2018

51st World Nursing Leadership & Management Conference

Moscow, Russia
October 08-10, 2018

33rd Euro Nursing & Medicare Summit

Edinburgh, Scotland
October 08-10, 2018 | Hilton Zurich Airport

5th International Conference on Gynecology and Obstetrics


Zurich, Switzerland
October 15-16, 2018 |

46th Global Nursing and Healthcare

Las Vegas, Nevada, USA
October 18-19, 2018

49th International Conference on Advanced Nursing Research

Amsterdam, Netherlands
October 19-20, 2018

42nd Nursing and Healthcare Congress

Ottawa, Canada
October 22-23, 2018

25th World Nursing and Nurse Practitioner Conference

Osaka, Japan
(10 Plenary Forums - 1 Event)
Oct 31-Nov 1, 2018

7th World Congress on Breast Cancer & Therapy

Columbus, USA
Oct 31-Nov 01, 2018

39th International Conference on Nursing & Healthcare

Columbus, Ohio, USA
November 05-07, 2018

5th World Holistic Nursing Conference

Abu Dhabi, UAE
November 07-08, 2018

6th World congress on Nursing Practice & Research

Alabama, USA
November 07-08, 2018

6th World congress on Nursing Leadership & Management

Alabama, USA
November 08-09 , 2018

25th World Congress on Nursing & Healthcare

Sydney, Australia
November 12-14, 2018

Annual Nursing Congress: The Art of Care

Istanbul, Turkey
November 12-14, 2018

27th World Nursing Education Conference

Berlin, Germany
November 19-21,2018

International Conference on Medicine, Nursing and Healthcare

Bucharest, Romania
November 19-21, 2018

International Conference on Community Nursing and Public Health

Cape Town, South Africa
December 03-04, 2018

52nd International Conference on Nursing and Health Care

Lisbon, Portugal
December 05-06, 2018

21st World Congress on Nursing Education and Management

Chicago, Illinois, USA
September 12-13, 2018

32nd International Conference on Nursing and Practice

Amsterdam, Netherlands
March 04-06, 2019

48th Global Nursing & Healthcare Conference

Barcelona, Spain
April 29-30, 2019

9th World Congress on Breast Cancer & Therapies

Kyoto, Japan
March 18-19, 2019

8th World Congress on Midwifery and Womens Health

Sydney, Australia
March 25-27, 2019

21st Global Nursing Education Conference

Orlando, USA
April 1-3, 2019

27th World Congress on Nursing Care

Auckland, Newzealand
April 10-11, 2019

4th World Congress on Nursing Education & Research

Toronto, Canada
April 22-23, 2019

3rd World Conference on Advanced Nursing Science & Practice

Houston, Texas, USA
April 25-26,2019

9th World Congress on Breast Cancer

London | UK
April 29-30, 2019

28th World Nursing Care Congress

Seoul, South Korea
May 17-18, 2019

4th International Conference on Nursing & Midwifery

Philadelphia, USA
April 10-11, 2019

4th World Congress on Nursing Practice & Research

Toronto, Canada
June 10-11, 2019

49th World Congress on Advanced Nursing Research

Berlin, Germany
August 12-13, 2019

Annual Midwifery and Pediatric Nursing Congress

Abu Dhabi, UAE

Innovative Therapeutic Apporaches in Breast Cancer Conference Speakers

Recommended Sessions

Related Journals

Are you interested in