Insulin and Beta Cell Targeting

Type2 diabetes mellitus is a chronic disease without cure. When beta-cell function progressively declines mostly, then blood glucose level rises only. However, recent studies have demonstrated remission of Type2 diabetes raising the possibility that the declining beta-cell function in Type2 diabetes may be arrested or even reversed, following bariatric surgery, intensive insulin therapy or very low-calorie diet. To focus on to early beta-cell preservation and people sickness remissions future treatment ways ought to be revised.

  • Effects of the incretions on β-cell mass
  • Targeting β-cell mass in type 2 diabetes
  • Targeting the pancreatic β-cell to treat diabetes
  • The incretion effect and its mediators
  • B-cell science
  • Implications for treatment

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