Lipid and Lipoprotein Metabolism

Lipoproteins can be produced endogenously in the liver with endogenous triglycerides and cholesterol in the hepatocytes, which are from chylomicron remnants. The LDL flows in the bloodstream and can be captivated by cells in the liver or peripheral tissues. The particles can fix to the target tissue with the LDL receptor with the engrossment of apolipoprotein B-100 which can then be engrossed by endocytosis, and the units hydrolyzed to discharge lipids such as cholesterol.

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