Marine Natural Products Drug Discovery

Drug discovery represents one of the most promising and highly visible outcomes of marine biotechnology research. Biochemicals produced by marine invertebrates, algae and bacteria, are very different than those from related terrestrial organisms and thus offer great potential as new classes of medicines. To date, examples of marine-derived drugs include antibiotics from fungi, two closely related compounds from a sponge that treat cancer and the herpes virus, and a neurotoxin from a snail that has painkiller properties making it 10,000 times more potent than morphine without the side effects. However, there are several more marine-derived compounds currently in clinical trials and it is likely that many more will advance to the clinic as more scientists look to the sea for these biotechnological uses. In addition to new medicines, other uses for marine-derived compounds include: cosmetics (algae, crustacean and sea fan compounds), nutritional supplements (algae and fish compounds), artificial bone (corals), and industrial applications (fluorescent compounds from jellyfish, novel glues from mussels, and heat resistant enzymes from deep-sea bacteria).

Primary research and market analysis shows sponges and marine animals to be the largest source of pharmaceutical products. In terms of geography, North America is expected to be the largest market for marine based pharmaceuticals. The history of marine-derived products began from cod-liver oil, shark oil, and calcium supplements. Marine biotechnology has developed over the years propelled by the unmet needs for new and innovative pharmaceutical products. Potential pipeline drugs being developed are anti-viral, anti-cancer drugs from byrozoans, anti-microbial, and anti-inflammatory. 

Marine natural products had become an established sub-discipline of natural products chemistry, and several thousand compounds had been described. Some groups of marine organisms were fairly well characterized for their major metabolites, and more often known compounds or their close relatives were being re-encountered. Emphasis on microorganisms has been rewarded with a wealth of new natural products chemistry, as well as the realization that many compounds previously isolated from macro organisms, such as sponges and tunicates, are actually metabolic products of associated microbes. As a result, a number of groups around the world have sought to culture marine bacteria from various sources, including shallow and deep water sediments, animate as well as inanimate surfaces, and from within the tissues of other macro organisms. 

  • Collection, biological screening and secondary testing
  • Production of material for clinical evaluation and investigation
  • Wading, scuba and trawling
  • Submersible collections
  • Innovative methodologies for isolation and structural elucidation
  • Marine novel metabolites
  • Current research methods in marine sources
  • Marine chemical ecology
  • Marine chemical warfare and human health
  • Marine sponges as sources of new drug leads
  • Process of marine and natural drug discovery

Related Conference of Marine Natural Products Drug Discovery

October 18-19, 2017

6th Global Congress on Mass Spectrometry

Osaka, Japan
October 19-20, 2017

9th Annual Congress on Drug Design & Drug Formulation

Seoul, South Korea
October 19-20, 2017

4th International Conference and Exhibition on Pain Medicine

(10 Plenary Forums - 1 Event)
San Francisco, California, USA
October 30-November 01, 2017
A B2B Networking & Global Knowledge Exchange Forum

Annual Congress on Emerging Orphan Drugs and  Rare Diseases

San Antonio, Texas, USA
November 13-14, 2017

Global Experts Meeting on Toxicology

Singapore
March 19-20, 2018

International Meeting on Nutraceuticals

Singapore
March 26-27, 2018

World Congress on Herbal and Chinese Medicine

Bali, Indonesia
April 20-21, 2018

4th International Conference on Antibiotics: R&D, B2B

Las Vegas, Nevada, USA
April 26-27, 2018

11th European Biosimilars Congress

Rome, Italy
May 07-09, 2018

15th Annual European Pharma Congress

Frankfurt, Germany
June 18-19, 2018

9th Global Experts Meeting on Neuropharmacology

Paris, France
June 20-22, 2018

7th World Congress on Mass Spectrometry

Rome, Italy
July 09- 10, 2018

Annual Meeting on Pharmacology

Bangkok, Thailand
July 09-10, 2018

12th Global
Pharmacovigilance & Clinical Trials Summit

Sydney, Australia
July 16-18, 2018

5th World Congress on Green Chemistry and Green Engineering

Melbourne, Australia
July 16-18, 2018

15th Asia-Pacific Pharma Congress

Melbourne, Australia
Jul 30-Aug 01, 2018

10th World Congress on Pharmacology

Barcelona, Spain
August 13-14, 2018

Global Experts Meeting on Case Reports

Tokyo, Japan
September 13-14, 2018

8th World Congress on Chromatography

Prague, Czech Republic
September 24-26, 2018

7th International Conference on Clinical Trials

Chicago, USA
(10 Plenary Forums - 1 Event)
October 22-23, 2018

18th Annual Pharma Middle East Congress

Abu Dhabi, UAE
Oct 29-30, 2018

3rd Global Pharma Congress

Osaka, Japan
November 05-06, 2018

18th Annual Pharmaceutical Chemical Analysis Congress

Madrid, Spain

Marine Natural Products Drug Discovery Conference Speakers

Recommended Sessions

Related Journals

Are you interested in