Mass Spectrometry in Proteome Research

Mass spectrometry (MS) - based proteomics allows the sensitive and accurate quantification of almost complete proteomes of complex biological fluids and tissues. At the moment, however, the routinely usage of MS-based proteomics is prevented and complicated by the very complex work flow comprising sample preparation, chromatography, MS measurement followed by data processing and evaluation. The new technologies, products and assays developed by Precision Proteomics could help enabling and establishing mass spectrometry (MS) - based proteomics in academic and pharmaceutical proteomics research as well as in clinical diagnostics.

  • Mass spectrometry for protein analysis
  • Tandem mass spectrometry (MS/MS)
  • Gas chromatography (GC) and liquid chromatography (LC)
  • High performance liquid chromatography (HPLC)
  • Mass spectrometry ionization methods
  • Mass spectrometry applications
  • Universal tools for mass spectrometry
  • Liquid chromatography mass spectrometry (LC-MS)
  • Multidimensional protein identification technology – MudPIT
  • Protein identification and validation
  • Over expression and purification of the proteins
  • Molecular imaging by mass spectrometry

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