Melanoma and Carcinoma Case Reports

A rare case of Amelanotic vulvar melanoma is presented. The patient was a 71-year-old woman complaining of vulvar itching and yellowish vaginal discharge who underwent a complete gynaecological evaluation during which a suspicious grey-whitish mass on her vulva was observed. The tumor presented superficial ulceration and was located in the upper half of the labia minor and clitoris. Initially it was suspected to be a vulvar carcinoma. Melanoma has the potential to metastasize to any organ in the body Patients with metastatic melanoma usually have a median survival of 6-9 months. We report a complete remission in an 80-year-old patient with malignant melanoma. The patient presented with pulmonary metastases and a history of multiple resections for local recurrence and in-transit metastasis. The sweat gland carcinoma is a rare tumor, representing in approximately 1% of primary skin lesions. In the literature 220 cases of sweat gland carcinomas have been presented over the last three decades. The medium age is 57 years, with an equal male-to-female distribution. 

Merkel cell carcinoma (MCC), also termed cutaneous small cell carcinoma or trabecular carcinoma is a rare tumor that most often presents as a solitary nodule on the head, neck, or extremities of older adults. It is an aggressive tumor that usually is fatal due to rapid metastasis. Sweat gland carcinoma is a rare skin tumor. The tumor has propensity to spread to lymph nodes and distant metastases has been reported. Primary mucosal melanoma is a rare and aggressive neoplasm, characterized by a higher aggressiveness and a worse prognosis than her cutaneous counterpart. The female genital tract is the second most common site of onset of mucosal melanoma; it represents the 3% of melanomas diagnosed in women. Melanoma, an aggressive, therapy-resistant malignancy of melanocytes, is the most serious type of skin cancer affecting young and middle-aged people. Therapy for early disease is predominantly surgical, with a minor benefit noted with the use of adjuvant therapy.

  • Amelanotic vulvar melanoma case report
  • Metastatic melanoma case report
  • Merkel cell carcinoma case report
  • Sweat gland carcinoma case report

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