Metabolic Disorders & Metabolomics

When abnormal chemical reactions occurs in your body and disrupt the process it is known as  metabolic disorder. There are different groups of disorders. Some affect the breakdown of amino acids, carbohydrates, or lipids. Another group, mitochondrial diseases, affects the parts of the cells that produce the energy. Metabolomics ,it is the study of low molecular weight molecules or metabolites  are found within cells and biological systems.  The metabolome is a measure of the inputs and outputs of biological pathways and it is often considered to more representative of the functional state of a cell than other ‘omics measures such as genomics or proteomics.  In addition, many metabolites are conserved across the  various animal species, facilitating the extrapolation of research findings in  the laboratory animals to humans.  Common technologies  are used for measuring the metabolome include the  mass spectrometry (MS) and  also nuclear magnetic resonance spectroscopy (NMR), which can detect  the hundreds to thousands of unique chemical entities (UCE).

  • Metabolic Profiling
  • Human Metabolome Database
  • Cysteine Modifications & Redoxomics
  • Metabolomic Database
  • Metabolomics Applications
  • Diabetes & Cardiovascular Diseases: Energy balance in disease phenotypes
  • Mass Spectrometry in Metabolomics
  • Metabolic Fingerprinting

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