Molecular Cytopathology

Molecular Cytopathology is an emerging discipline within Cytopathology which is focused on the study and diagnosis of disease through the examination of molecules within organs, tissues or bodily fluids. Clinical pathology is a medical specialty that is concerned with the diagnosis of disease based on the laboratory analysis of bodily fluids, such as blood, urine, and tissue homogenates or extracts using the tools of chemistry, microbiology, hematology and molecular pathology. Cervical cancer is the third most common type of cancer among women worldwide. The infection and persistence of human papillomavirus (HPV) are the essential conditions for this type of disease. However, only HPV infection is not enough for cervical pathogenesis are necessary cofactors and activation of intracellular and extracellular mechanisms to start.

In the conventional Pap smear, the physician collecting the cells smears them on a microscope slide and applies a fixative. In general, the slide is sent to a laboratory for evaluation. The studies include Liquid-based monolayer cytology and Human papillomavirus testing. Diagnostic molecular pathology: Recent revolutionary progress in human genomics is reshaping our approach to therapy and diagnosis

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