Molecular Pathology

Molecular pathology is a discipline that focus on the study and diagnosis of disease by the examination of molecules in organs, tissues or bodily fluids. It focuses mainly on the sub-microscopic aspects of the disease. It also shares some aspects of practice with anatomic pathology, clinical pathology, molecular biology, biochemistry, proteomics and genetics, and is considered as "crossover" discipline. The purpose of molecular pathology is to elucidate the mechanisms of disease by identifying molecular and pathway alterations. Molecular pathology is commonly used in the diagnosis of cancer and infectious diseases. Techniques like quantitative polymerase chain reaction (qPCR), multiplex PCR, DNA microarray, in situ hybridization, in situ RNA sequencing, DNA sequencing, molecular profiling of pathogens, and analysis of bacterial genes for antimicrobial resistance are used for diagnosis of diseases

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