Named Rearrangements and Reactions

A rearrangement reaction is a broad class of organic reactions where the carbon skeleton of a molecule is rearranged to give a structural isomer of the original molecule. Often a substituent moves from one atom to another atom in the same molecule. In the example below the substituent R moves from carbon atom 1 to carbon atom 2. A rearrangement is not well represented by simple and discrete electron transfers represented by curly arrows in organic chemistry texts. The actual mechanism of alkyl groups moving, as in Wagner-Meerwein rearrangement, probably involves transfer of the moving alkyl group fluidly along a bond, not ionic bond-breaking and forming. In pericyclic reactions, explanation by orbital interactions give a better picture than simple discrete electron transfers. It is, nevertheless, possible to draw the curved arrows for a sequence of discrete electron transfers that give the same result as a rearrangement reaction, although these are not necessarily realistic. In allylic rearrangement, the reaction is indeed ionic.

A rearrangement reaction is a broad class of organic reactions where the carbon skeleton of a molecule is rearranged to give a structural isomer of the original molecule. Often a substituent moves from one atom to another atom in the same molecule. In the example below the substituent R moves from carbon atom 1 to carbon atom 2. A rearrangement is not well represented by simple and discrete electron transfers represented by curly arrows in organic chemistry texts. The actual mechanism of alkyl groups moving, as in Wagner-Meerwein rearrangement, probably involves transfer of the moving alkyl group fluidly along a bond, not ionic bond-breaking and forming. In pericyclic reactions, explanation by orbital interactions give a better picture than simple discrete electron transfers. It is, nevertheless, possible to draw the curved arrows for a sequence of discrete electron transfers that give the same result as a rearrangement reaction, although these are not necessarily realistic. In allylic rearrangement, the reaction is indeed ionic.

  • Methods and applications of Claisen Rearrangement and Condensation
  • Methods and applications of wittig rearrangement, Wurtz-Fittig reaction
  • Methods and applications of Cope rearrangement, Kolbe-Schmitt reaction
  • Methods and applications of Suzuki Coupling reactions, Paal-Knorr Pyrrole synthesis
  • Methods and applications of Benzilic Acid rearrangement
  • Methods and applications of Hofmann Elimination reactions

Related Conference of Named Rearrangements and Reactions

Named Rearrangements and Reactions Conference Speakers