Neuro-immune interaction

The inflammatory response is modulated through interactions among the nervous, endocrine, and immune systems. Intercommunication between immune cells and the autonomic nervous system is a growing area of interest .Spatial and temporal information about inflammatory processes is relayed to the central nervous system where neuroimmune modulation serves to control the extent and intensity of the inflammation. The CNSregulates the immune system via hormonal and neuronal pathways, including the sympathetic and parasympathetic nerves. The immune system signals the CNS through cytokines that act both centrally and peripherally.

The neuroimmune system is a system of biochemical and electrophysiological interactions between the nervous system andimmune system. It serves to protect neurons in the brain and body against disease by maintaining selectively permeable barriers, mediating neuroinflammation and wound healing, and mobilizing host defenses against pathogens.The neuro-immune system, and study of, comprises an understanding of the immune and neurological systems and the cross-regulatory impacts of their functions. Cytokines regulate immune responses, possibly through activation of the hypothalamic-pituitary-adrenal (HPA) axis.There is growing evidence that auto-immune T-cells are involved in neurogenesis. Studies have shown that during times of adaptive immune system response, hyppocampal neurogenesis is increased, and conversely that auto-immune T-cells and microglia are important for neurogenesis  in healthy adults.

  • Corticosteroids-hormonal signaling
  • CNS parenchyma
  • Innate immune response
  • Immune response
  • Epigenetics of neuroimmunology
  • Pathogenesis of immune-mediated neurological disorders

Related Conference of Neuro-immune interaction

Neuro-immune interaction Conference Speakers