Neurogenesis and Gliogenesis

Neurogenesis is the technique by using which new neurons are formed within the brain. Neurogenesis is essential when an embryo is growing, but also continues in certain brain areas after delivery and in the course of our lifespan. The mature brain has many specialized areas of function, and neurons that differ in shape and connections. Gliogenesis is the developmental method by using which glial cells – astrocytes, oligodendrocytes, Schwann cells and microglia – are generated. It consists of the production of glial progenitor cells and their differentiation into mature glia. Gliogenesis results in the formation of non-neuronal glia populations derived from multipotent neural stem cells. In this ability, glial cells offer a couple of functions to both the central nervous system (CNS) and the peripheral nervous system (PNS). Subsequent differentiation of glial cell populations results in function-specialised glial lineages.

 

  • Nervous system patterning and developmental cell death
  • Cell lineage
  • Mechanisms of cell fate
  • Neuronal differentiation
  • Glial differentiation and interaction with neurons

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