Neurohormones and Heart Failure

Neurohormones are an assortment of many chemical messengers of cardiac and extra cardiac origin that are found at high circulating levels in adults with chronic heart failure (CHF). Neurohormonal systems are normally stimulated under conditions of acute volume depletion, activated by cardiac output and blood pressure. However, prolonged and chronic activation of these systems may result in progressive ventricular remodeling and worsening of heart failure, as occurs in congestive heart failure (CHF).

  • Congenital heart disease
  • Angiotensin-Converting Enzyme inhibitor therapy
  • Pathophysiology of chronic heart failure (CHF)

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