Peripheral nerve injuries

Peripheral nerve damage is characterised in the Seddon classification based on the extent of damage to both the nerve and the surrounding connective tissue since the nervous system is characterized by the necessity of neurons on their supporting glia. Unlike in the central nervous system, regeneration in the peripheral nervous system is possible.] The processes that occur in peripheral regeneration can be separated into the following major events: Wallerian degeneration, axon regeneration/growth, and nerve reinnervation. The events that occur in peripheral regeneration arise with respect to the axis of the nerve injury. The proximal stump refers to the end of the injured neuron that is still attached to the neuron cell body; it is the part that regenerates. The distal stump refers to the end of the damaged neuron that is still attached to the end of the axon; it is the part that will degenerate but remains the area that the regenerating axon grows toward.

  • Relevant anatomy
  • Pathology
  • Mechanism of injury
  • Electrodiagnostic studies
  • Prognosis

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