Pharmaceutical Analysis Errors and Validation

Analytical errors are fundamental before submitting your report and results with the required level of confidence. However, we should have clarity regarding accuracy and precision before we are talking pharmaceutical error. Most of us believe that these terms have the same meaning but the example of arrows striking a target. Any measurement is limited by the precision of the measuring instruments and the technique and the skill of the observer. Where a measurement consists of a single reading on a simple piece of laboratory equipment, for example, a burette or a thermometer, one would expect the quantity of factors adding to vulnerabilities in that estimation to be less than an estimation which is the consequence of a multi-step process comprising of at least two weight estimations, a titration and the utilization of an variety of reagents.

 

  • Determinate errors
  • Indeterminate errors
  • Statistical treatment of finite samples
  • Sampling statistics

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