Pharmaceutical Chemistry Novel Aspects

Pharmaceutical chemistry is a branch at the intersection of chemistry, especially synthetic organic chemistry, and pharmacology and various biological specialties, where they participate in the design of drugs, chemical synthesis and development for the market, or bioactive molecules (drugs). In particular, pharmaceutical chemistry in its most common guideline focusing on small molecules / organic entities encompasses synthetic organic chemistry and aspects of natural product chemistry and computational chemistry in close combination with chemical biology, enzymology and structural biology, together with the goal of discovery and drug development of new different therapeutic agents. Speaking in practical terms, it involves chemical aspects of identification and, subsequently, a systematic and exhaustive synthetic alteration of new chemical entities to make them appropriate for therapeutic use. It includes synthetic and computational aspects of the study of drugs and agents existing in the development in relation to their biological activities (activities and biological properties), that is, the understanding of their structure-activity relationships (SAR). Pharmaceutical chemistry focuses on the quality aspects of medicines and aims to ensure the adequacy of the purposes of the medicines.

  • Physicochemical and biological factors that contribute to drug action

  • Medicinal Radio compounds or Radiopharmaceuticals

  • Global Pharmaceutical Policy

  • Impurities and Impurity Profile Significance in API

  • Design of Safer Chemicals and Products

  • Process Chemistry Considerations

  • Structure-activity relationships of drug Moiety

  • Synthetic chemistry including combinatorial methods

  • In vivo and in vitro biotransformations of drugs

  • Modeling and designing of small compounds

  • Physicochemical and biological factors that contribute to drug action

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