Prostaglandins and Leukotrienes

Many cell types synthesize prostaglandins and leukotriene from arachidonic acid, a polyunsaturated fatty acid component of phospholipids. Two cyclooxygenase isoenzymes are COX-1 and COX-2. Pro-inflammatory effects in isolation, prostaglandins PGE2 and PGD2 promote vasodilatation. Leukotriene’s C4, D4, E4 may cause bronchial constriction .They enhance vascular permeability. It also includes Pharmacology cross reference, Cortisol and related glucocorticosteroids inhibition of cyclooxygenases (COX), acetylsalicylic acid (Aspirin®) and other NSAIDs

  • Cross reference
  • Cortisol
  • Glucocorticosteroids
  • Acetylsalicylic acid

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