Resistant Depression Treatment

Treatment-resistant depression poses a significant challenge for psychiatrists. According to an interactive session presented at the American Psychiatric Association Annual Meeting cognitive behavioral therapy may be an effective method for cutting through barriers to care in those hard-to-treat cases. CBT has shown to reduce the suicidal behavior compared with standard treatment. CBT affects despair and hopelessness and gives a sense of hope to go on. Goal setting is an important aspect of CBT therapy for treatment-resistant depression. Knowing  patients view on  how they would like to see their life change as a result of treatment, or what they'd do differently if they weren't depressed, introduces patients to new, more positive perspectives.

Treatment-resistant depression (TRD) or treatment-refractory depression is a term used in clinical psychiatry to describe cases of major depressive disorder (MDD) that do not respond adequately to appropriate courses of at least two antidepressants. Many clinicians consider a response inadequate if the patient does not achieve full remission of symptoms. Cases of treatment-resistant depression in which the course of treatment was not adequate are sometimes referred to as pseudoresistant. Some factors that contribute to inadequate treatment are: early discontinuation of treatment, insufficient dosage of medication, patient noncompliance, misdiagnosis, and concurrent psychiatric disorders.

  • Medication strategies
  • Psychological counseling
  • Vagus nerve stimulation
  • Transcranial magnetic stimulation
  • Dialectical behavioral therapy.
  • Psychodynamic treatment

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