Reward deficiency syndrome and Animal models

Inability to produce or utilize "feel good" chemicals from serotonin and dopamine, to norepinephrine, GABA and endorphins is termed as Reward Deficiency Syndrome. Neuroscientifically, when levels of these "feel good" chemicals are low or blocked from the brain's receptors it results in pain, discomfort and agitation. Reward deficiency is associated with mood instability, anxiety, hypersensitivity and irritability.
  • Introduction to Reward Deficiency Syndrome
  • Neuroscience and Reward Deficiency Syndrome
  • Relapse and prevention strategies
  • Animal models and human comparison

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