Semaphorins as Regulators of Chronic Mucosal Inflammatory Conditions

Semaphorins are a large family of proteins involved in the pathogenesis of inflammatory diseases through the regulation of immune homeostasis and tissue inflammation. Several members of semaphorin family proteins have been recently defined as active and non-redundant players in the inflammatory response regulating immune cells, smooth muscle cells, endothelial cells and eosinophils.

Semaphorins are a large family of proteins involved in the pathogenesis of inflammatory diseases through the regulation of immune homeostasis and tissue inflammation. Several members of semaphorin family proteins have been recently defined as active and non-redundant players in the inflammatory response regulating immune cells, smooth muscle cells, endothelial cells and eosinophils. 

  • Immune Semaphorins in Intestinal Inflammation
  • Semaphorins and their Receptors in Immune Cell Interactions and Inflammation
  • Regulation of Pulmonary Inflammation by Semaphorin 7A
  • Semaphorins as Regulators of Tumor Progression and Tumor Angiogenesis
  • Semaphorin 7A in Pulmonary Fibrosis
  • Semaphorins 4A and 4D in Asthma Pathogenesis
  • Semaphorin 3E in Airway Smooth Muscle Function

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