Structural and Molecular Parasitology

Structural parasitology is the study of structures of parasitic proteins.  Among protozoan parasites, the phylum of Apicomplexa includes organisms responsible for malaria, toxoplasmosis and cryptosporidiosis.  Trypanosoma and Leishmania parasites, belonging to the phylum of Kinetoplastida, cause Chagas disease, African Sleeping Disease and visceral leishmaniasis.  For some of these diseases, such as malaria, existing drugs face the threat of resistance.  For others, such as cryptosporidiosis, there is no effective chemotherapy.

 

Molecular Parasitology involves molecular biology and biochemistry of parasitic worms and helminths and their interactions with both the definitive and intermediate host. The main subject areas covered are the structure, biosynthesis, degradation, properties and function of DNA, RNA, proteins, lipids, carbohydrates and small molecular-weight substances, drug target characterization and the mode of action of antiparasitic agents. 

 
  • Structural Biology
  • Structure & Functionality of Proteins
  • Gene Expression
  • Genetic Diversity
  • Applications of Molecular Techniques in Parasitology
  • Mechanisms of Viral Transmission

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