Structural Biochemistry and Single Molecules

Structural Biochemistry is a subdivision of biochemistry that combines biology, physics, and chemistry, mainly focused on the components, structures and functions of molecules within cells that make up the living organisms.

Single-molecule studies may be contrasted with measurements on an ensemble or bulk collection of molecules, where the individual behavior of molecules cannot be distinguished and only average characteristics can be measured. To study the individual biomolecules, biophysical methods have been developed. Thus it enables the biologist to monitor all the biological process and helps in understanding the underlying mechanism. Further, removal of ensemble average and fluctuations catalytic properties can be elucidated. Advancements like applying force on the biomolecules helps to obtain important information like how proteins couples function to structure.

  • Glycolysis and Gluconeogenesis
  • Foundational microorganism
  • Linear combination of atomic orbitals
  • Biophysics- Single molecule techniques
  • Stereochemistry of organic molecules
  • Structural biochemistry of DNA & RNA
  • Folding
  • Channels and Transporters
  • Enzyme Catalysis

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