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Journal of Drugs and Toxins is a peer reviewed Journal that focuses on the publication of advancements in the field of Drug Safety and Toxicology by encompassing broad areas including ethical practices and safety in drug production, delivery and distribution and their implications in maintaining the public health.
The Journal focuses on the latest research developments in this field by including research on topics like Safety Toxicology, Drug Safety, Epidemiology, Drug toxicity, Poisoning, Antidotes, Xenobiotics, Pharmacovigilance, and adverse drug reactions.
The Journal accepts original manuscripts in the form of research article, review article, short communication, case report, letter-to-the-Editor and Editorials for publication. All the published articles are open access and can be accessed online without any subscription charges. The Journal extensively enhances the worldwide visibility of the scholars that contribute their research work.
The Editorial Manager System helps in maintaining the quality of the peer review process and enables the authors to track the review and publication process in an automated way. Experts in the field of Drugs and Toxins take up the review process under the guidance of Editor-in-Chief. Approval of at least two independent reviewers and the editor is mandatory for the acceptance of the manuscript for publication.
Authors may submit manuscripts and track their progress through the system, hopefully to publication. Reviewers can download manuscripts and submit their opinions to the editor. Editors can manage the whole submission/review/revise/publish process.
Adverse Drug Reaction as “an appreciably harmful or unpleasant reaction, resulting from an intervention related to the use of a medicinal product, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product.”
ADR are classified into six types (with mnemonics): dose-related (Augmented), non-dose-related (Bizarre), dose-related and time-related (Chronic), time-related (Delayed), withdrawal (End of use), and failure of therapy (Failure).
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Biomarkers are biological measures of a biological state. A biologic feature that can be used to measure the presence or progress of disease or the effects of treatment.
Examples of Biomarkers might include levels of proteins in the blood, patterns of activity in the brain, or the amount of time it takes for an individual to complete a task. The heterogeneous nature of Autism Spectrum Disorders has made the identification of an autism biomarker a difficult task. Currently, physicians do not use biomarker measurements in the clinic to predict the onset of autism in children. Early intervention in children with autism is known to improve behavioral outcomes. Because biomarkers may help identify children with autism earlier in infancy, autism biomarker identification is an area of intense interest. Brain imaging studies, in particular, have shown promising results.
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Biomonitoring is the use of biological responses to assess changes in the environment, generally changes due to anthropogenic causes. Biomonitoring programs may be qualitative, semi-quantitative, or quantitative. Biomonitoring is a valuable assessment tool that is receiving increased use in water quality monitoring programs of all types.
Related Journals of Biomonitoring
Environmental Monitoring and Assessment, Journal of Occupational & Environmental Medicine, Journal of Environmental Health Science and Engineering, Environmental Science: Processes & Impacts, Journal of Toxicology and Environmental Health
Biopharmaceuticals are medical drugs produced using biotechnology. They are proteins (including antibodies), nucleic acids (DNA, RNA or antisense oligonucleotides) used for therapeutic or in vivo diagnostic purposes, and are produced by means other than direct extraction from a native (non-engineered) biological source.
Related Journals of Biopharmaceuticals
European Journal of Pharmaceutics and Biopharmaceutics,Journal of Biopharmaceutical Statistics, Clinical Pharmacology & Biopharmaceutics, Journal of Biopharmaceutics and Biotechnology, International Journal of Biopharmaceutics, Journal of Biopharmaceutical Statistics
It is a metabolic syndrome that results from the accumulation of lipid intermediates in non-adipose tissue, leading to cellular dysfunction and death. The tissues normally affected include the kidneys, liver, heart and skeletal muscle. Lipotoxicity is believed to have a role in heart failure, obesity, and diabetes, and is estimated to affect approximately 25 % of the adult American population.
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Nephrotoxicity is toxicity in the kidneys. It is a poisonous effect of some substances, both toxic chemicals and medications, on renal function. There are various forms, and some drugs may affect renal function in more than one way. Nephrotoxins are substances displaying nephrotoxicity.
Related Journals of Nephrotoxicity
International Journal of Basic & Clinical Pharmacology, Advances in Pharmacoepidemiology & Drug Safety, Journal of Cancer Science & Therapy, Journal of Urology and Nephrology
Neurotoxicity is toxicity in the nervous system. It occurs when exposure to natural or artificial toxic substances, which are called neurotoxins, alters the normal activity of the nervous system in such a way as to cause damage to nervous tissue. This can eventually disrupt or even kill neurons, key cells that transmit and process signals in the brain and other parts of the nervous system. Neurotoxicity can result from exposure to substances used in chemotherapy, radiation treatment, drug therapies, certain drug abuse, and organ transplants, as well as exposure to heavy metals, certain foods and food additives, pesticides, industrial and/or cleaning solvents, cosmetics, and some naturally occurring substances. Symptoms may appear immediately after exposure or be delayed. They may include limb weakness or numbness, loss of memory, vision, and/or intellect, uncontrollable obsessive and/or compulsive behaviors, delusions, headache, cognitive and behavioral problems and sexual dysfunction. Individuals with certain disorders may be especially vulnerable to neurotoxins.
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Network medicine is the application of network science towards identifying, preventing, and treating diseases. This field focuses on using network topology and network dynamics towards identifying diseases and developing medical drugs. Biological networks, such as protein-protein interactions and metabolic pathways, are utilized by network medicine. Disease networks, which map relationships between diseases and biological factors, also play an important role in the field. Epidemiology is extensively studied using network science as well; social networks and transportation networks are used to model the spreading of disease across populations.
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Pharmacokinetic is the branch of pharmacology that studies the fate of pharmacological substances in the body, as their absorption, distribution, metabolism, and elimination.
Related Journals of Pharmacokinetics
Journal of Pharmacokinetics and Pharmacodynamics, Drug Metabolism and Pharmacokinetics, International Journal of Pharmacokinetics, Journal of Pharmacokinetics & Experimental Therapeutics, Journal of Pharmacokinetics and Pharmacodynamics
Toxinology is the specialized area of science that deals specifically with animal, plant, and microbial toxins. Toxinology has been defined as "the scientific discipline dealing with microbial, plant and animal venoms, poisons and toxins". "Toxinology includes more than just the chemistry and mode of action of a toxin. It deals also with the biology of venom- or poison-producing organism, the structure and function of the venom apparatus, as well as the use of the venom or poison, the ecological role of these compounds".Toxinology has also been defined as "the science of toxic substances produced by or accumulated in living organisms, their properties, and their biological significance for the organisms involved".
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Validation is a process of establishing documentary evidence demonstrating that a procedure, process, or activity carried out in production or testing maintains the desired level of compliance at all stages. In Pharma Industry it is very important apart from final testing and compliance of product with standard that the process adapted to produce itself must assure that process will consistently produce the expected results
Related Journals of Validation (Drug Manufacture)
International Journal of Pharma and Bio Sciences, International Journal of Pharmaceutical Sciences and Research, Tropical Journal of Pharmaceutical Research, Journal of Pharmaceutical Quality Assurance,
Viral pathogenesis is the study of how biological viruses cause diseases in their target hosts, usually carried out at the cellular or molecular level. It is a specialized field of study in virology. Pathogenesis is a process in which an initial infection becomes a disease. Viral disease is a sum of the effects on the host caused by the replication of the virus and of the host's subsequent immune response.
Related Journals of Viral pathogenicity
Journal of Technology and Medicine, Journal of Virology, Journal of Microbial Pathogenesis