Viruses are obligate intracellular parasites as they are necessarily dependent upon specific host cells for their survival. This principle leads to the development of a drug delivery system that mimics the viral pattern of cellular infection.Apart from the targeted delivery of therapeutic agents, virosomes preserve the stability and activity of active agents. Therapeutic molecules get degraded by the endosome lysosomal degradation mechanisms before reaching the target cells in case conventional drug delivery procedures are utilized.However, if virosome can reach the site of action within a short time of administration in the body, efficient drug delivery can be predicted.Furthermore, once inside the cells, the virosomes do not replicate, ensuring their safety profile.he surface glycoproteins of influenza virus, hepatitis viruses and vesicular stomatitis virus have been successfully incorporated in a number of vaccine and drug delivery systems. Virosomes containing cancer chemotherapeutic agents, antimalarial, antibacterial and antifungal agents have shown efficient release profiles in vitro and in vivo. Based upon the same principle, bacterial ghosts have been developed. (MustafeezMujtaba Babar, ajam-us-SaharSadafZaidi, AlvinaGulKazi and Abdul Rehman, Virosomes-Hybrid Drug Delivery Systems)
Academic journals are periodicals in which researchers publish their findings, mostly the recent ones. Academic journals are typically peer-reviewed journals that publish theoretical discussions and articles that critically review already published work. Academic journals serve as an important forum for researchers and academicians from where they can access important information about recent developments in their field. These journals are the first choice for any in-depth examination of an issue related to science. Science as we know is scarcely imaginable without the academic journal. OMICS Group International Journals fall under the academic category as they strictly adhere to peer-review process and follow the format by publishing mostly the original work.
Last date updated on July, 2014