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Christopher Edward Mason, is an assistant professor of Computational Genomics at Weill Cornell Medical College. He completed his B.S In Genetics and Biochemistry from University of Wisconsin-Madison and Ph.D in Genome Evolution and postdoctoral in Neuroscience from Yale University. His laboratory work utilizes computational and experimental methodologies to identify and characterize the essential genetic elements that guide the function of the human genome. He perform research in three principal areas: (1) the functional annotation of the human genome by mutational profiling in families with brain malformations and cancer patients, (2) the examination of the elements that orchestrate the development of the human brain and their evolutionary changes, and (3) the development of models for systems and synthetic biology. We use high-throughput methods to generate cell-specific molecular maps of genetic, epigenetic, and transcriptional activity and we use them to create multi-dimensional molecular portraits of development and disease. We develop algorithms to detect, catalog and functionally annotate variants in the genetic pathways that control developmental processes. He has more than 50 publications.
Brain malformations and cancer, Human brain and their evolutionary changes, High-throughput methods
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